Article
CD1-Restricted T Cell Recognition of Microbial Lipoglycan Antigens
14 Jul 1995
Abstract excerpt
It has long been the paradigm that T cells recognize peptide antigens presented by major histocompatibility complex (MHC) molecules. However, nonpeptide antigens can be presented to T cells by human CD1b molecules, which are not encoded by the MHC. A major class of microbial antigens associated with pathogenicity are lipoglycans. It is shown here that human CD1b presents the defined mycobacterial lipoglycan...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
