Article
Characterization of Japanese families with early-onset type 2 (non-insulin dependent) diabetes mellitus and screening for mutations in the glucokinase and mitochondrial tRNA(Leu(UUR)) genes.
Acta diabetologica - 1 Mar 1995
Iwasaki N, Ohgawara H, Nagahara H, Kawamura M, Bell G I, Omori Y
Abstract excerpt
Genetic linkage studies of families with early-onset type 2 diabetes have facilitated the identification of diabetes-susceptibility genes. In order to assess the feasibility of using linkage approaches to identify genes responsible for the development of type 2 diabetes in Japanese subjects, we e...
Topics
- Adolescent
- Adult
- Age of Onset
- Aged
- Base Sequence
- Codon
- DNA Primers
- Diabetes Mellitus, Type 2
- Female
- Genetic Linkage
- Glucokinase
- Glucose Tolerance Test
- Humans
- Japan
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation