Article
Interaction of a Tyrosine Kinase from Human Sperm with the Zona Pellucida at Fertilization
7 Jul 1995
Abstract excerpt
A 95-kilodalton mouse sperm protein with characteristics of a protein tyrosine kinase has been identified as a receptor for ZP3, a glycoprotein in the egg's extracellular matrix. The structure of the human homolog was determined by screening an expression library from human testis; a testis-specific complementary DNA was isolated that encodes a protein similar to receptor tyrosine kinases and appears to be...
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