Molecular genetics of Huntington's disease.

doi:10.1001/archneur.1993.00540110037003

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Article

Molecular genetics of Huntington's disease.

Archives of neurology - 1 Nov 1993

Gusella J F, MacDonald M E, Ambrose C M, Duyao M P

Abstract excerpt

Huntington's disease is an inherited disorder in which selective neuronal loss in the brain leads to a characteristic choreic movement disorder. The successful mapping of the Huntington's disease gene to chromosome 4 set off a torrent of similar studies in other inherited disorders as investigato...

Topics

Amino Acid Sequence
Chromosomes, Human, Pair 4
DNA
Genetic Markers
Humans
Huntington Disease
Molecular Biology
Molecular Sequence Data
Mutation
Nucleotides
Repetitive Sequences, Nucleic Acid

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