N- and KRAS mutations in primary testicular germ cell tumors: incidence and possible biological implications.

doi:10.1002/gcc.2870120205

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Article

N- and KRAS mutations in primary testicular germ cell tumors: incidence and possible biological implications.

Genes, chromosomes & cancer - 1 Feb 1995

Olie R A, Looijenga L H, Boerrigter L, Top B, Rodenhuis S, Langeveld A, Mulder M P, Oosterhuis J W

Abstract excerpt

Recently, conflicting results have been reported on the incidence of RAS mutations in primary testicular germ cell tumors of adults (TGCTs). In four studies a low incidence of mutations (less than 15%) in a variety of TGCTs or derived cell lines was found, whereas in two other studies a high inci...

Topics

Alleles
DNA, Neoplasm
Genes, ras
Germinoma
Humans
Male
Mutation
Polymerase Chain Reaction
Testicular Neoplasms

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