Article
RFLP analysis of human chromosome 11 region q13 in multiple symmetric lipomatosis and multiple endocrine neoplasia type 1-associated lipomas.
Biochemical and biophysical research communications - 6 Feb 1995
Morelli A, Falchetti A, Weinstein L, Fabiani S, Tomassetti P, Enzi G, Carraro R, Bordi C, Tonelli F, Brandi M L
Abstract excerpt
Six lipomas from patients affected by Multiple Symmetric Lipomatosis (MSL) and by Multiple Endocrine Neoplasia Type 1 (MEN 1) were analyzed for loss of heterozygosity on chromosome 11 region q12-13 using four RFLPs. Allelic loss for the D11S146 locus was found only in one visceral MEN 1-associate...
Topics
- Alleles
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Codon
- DNA Primers
- Deoxyribonuclease HpaII
- Deoxyribonucleases, Type II Site-Specific
- GTP-Binding Proteins
- Humans
- Lipoma