Article
The human HNP36 gene is localized to chromosome 11q13 and produces alternative transcripts that are not mutated in multiple endocrine neoplasia, type 1 (MEN I) syndrome.
Genomics - 1 Jun 1997
Williams J B, Rexer B, Sirripurapu S, John S, Goldstein R, Phillips J A, Haley L L, Sait S N, Shows T B, Smith C M, Gerhard D S
Abstract excerpt
Multiple endocrine neoplasia, type 1 (MEN I), is an autosomal dominant syndrome of selected endocrine neoplasms whose causative gene, a suspected tumor suppressor, has been localized to chromosome 11q13, but has not been identified. Recently, the HNP36 cDNA was identified as a novel growth factor responsive gene of undetermined biological function that is expressed in the pituitary and parathyroid glands. In...
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