Article
Binding of Pseudomonas aeruginosa to respiratory epithelial cells from patients with various mutations in the cystic fibrosis transmembrane regulator.
The Journal of pediatrics - 1 Feb 1995
Zar H, Saiman L, Quittell L, Prince A
Abstract excerpt
OBJECTIVE: To determine whether there is an association between mutations of the cystic fibrosis transmembrane regulator (CFTR) and the predilection of patients with cystic fibrosis (CF) for Pseudomonas aeruginosa infection. METHOD: We quantified the adherence of P. aeruginosa PA01, labeled with sulfur 35-methionine, to epithelial monolayers derived from nasal scrapings of patients with specific CFTR mutations,...
Topics
- Adolescent
- Adult
- Bacterial Adhesion
- Cells, Cultured
- Chloride Channels
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Disease Susceptibility
- Epithelial Cells
- Epithelium