Article
Inflammation in cystic fibrosis airways: relationship to increased bacterial adherence.
The European respiratory journal - 1 Jan 2001
Scheid P, Kempster L, Griesenbach U, Davies J C, Dewar A, Weber P P, Colledge W H, Evans M J, Geddes D M, Alton E W
Abstract excerpt
It is unclear whether inflammation in the cystic fibrosis (CF) lung relates predominantly to bacterial infection, or occurs as a direct consequence of mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein. Interleukin (IL)-8 secretion from CF and non-CF cell lines, and from CF and non-CF human primary nasal epithelial cells incubated with or without Pseudomonas aeruginosa, was measured....
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