Article
CFTR mutations and host susceptibility to Pseudomonas aeruginosa lung infection.
Current opinion in microbiology - 1 Feb 2002
Pier Gerald B
Abstract excerpt
The susceptibility of cystic fibrosis patients to bacterial pathogens is associated with deficient airway antimicrobial peptide activity, and airway-surface-liquid dehydration with decreased transport velocity and hypersecretion of mucus. Susceptibility to Pseudomonas aeruginosa infection has been linked to the role of the cystic fibrosis transmembrane conductance regulator protein as a receptor for P....
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