Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The development of T and non-T cell lineages from CD34+ human thymic precursors can be traced by the differential expression of CD44.

The Journal of experimental medicine - 1 Feb 1995

Márquez C, Trigueros C, Fernández E, Toribio M L

Abstract excerpt

In addition to T-lineage cells, a small proportion of hematopoietic non-T cells are present in the human postnatal thymus. However, the origin of this minor non-T cell thymic compartment is presently unknown. In this study we have analyzed the developmental potential of the earliest human intrathymic precursors, characterized as CD34+ cells expressing intermediate levels of CD44. We show that these CD34+CD44int...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Child, Preschool

Share to Infant

Share to Phenotype

Share to Receptors, Cell Surface

Share to T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 7530757
DOI: 10.1084/jem.181.2.475
PMCID: PMC2191886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The development of T and non-T cell lineages from CD34+ human thymic precursors can be traced by the differential expression of CD44.PMID 7530757Read ↗

Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potentialSemantic proximity Read ↗

A human postnatal lymphoid progenitor capable of circulating and seeding the thymus.Semantic proximity Read ↗

Notch1 and IL-7 Receptor Interplay Maintains Proliferation of Human Thymic Progenitors while Suppressing Non-T Cell FatesSemantic proximity Read ↗

[Phenotypic and functional characterization of human prothymocytes].Semantic proximity Read ↗

Early T Lymphocyte ProgenitorsSemantic proximity Read ↗

Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development.Semantic proximity Read ↗

Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7- lympho-myeloid thymic progenitors.Semantic proximity Read ↗

Development of a method of thymocyte differentiation of bone marrow-enriched CD34+CD38- cells in postnatal allogeneic cultured thymic epithelia to evaluate immunodeficiency disorders.Semantic proximity Read ↗

Identification of human T-lymphoid progenitor cells in CD34+ CD38low and CD34+ CD38+ subsets of human cord blood and bone marrow cells using NOD-SCID fetal thymus organ cultures.Semantic proximity Read ↗

Dynamics of thymus organogenesis and colonization in early human developmentSemantic proximity Read ↗

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profilingSemantic proximity Read ↗

Functional and phenotypic analysis of thymic CD34+CD1a- progenitor-derived dendritic cells: predominance of CD1a+ differentiation pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.