Article
CHO.K1 cell mutants sensitive to active oxygen-generating agents. I. Isolation and genetic studies.
Mutation research - 1 Nov 1994
Hama-Inaba H, Shimazu Y, Takusagawa M, Sato K, Morimyo M
Abstract excerpt
Nine mutants isolated from CHO.K1 cells with increased sensitivity to the lethal effect of plumbagin (PG), a powerful superoxide generator, were classified into five groups, A-E, according to their sensitivity to PG and methyl viologen (MV). Two mutants of group B (Pa13 and Pb4) were sensitive to both drugs, and two mutants of group C (Pa14 and Pa15) were moderately sensitive to PG and extremely sensitive to MV....
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