Article
Singlet oxygen production and photobiological effects of pinacyanol chloride on yeast Saccharomyces cerevisiae.
Journal of pharmacobio-dynamics - 1 May 1990
Iwamoto Y, Murakami K, Danno M, Tsuchiya M, Masuzawa T, Shimizu T, Morita T, Yanagihara Y
Abstract excerpt
Photobiological activities of pinacyanol chloride (PC), which is known as a non-intercalating dye, were investigated. Irradiation of PC-sensitized yeast cells in the dark brought about marked decrease of survival and induction of "petites" which are respiration-deficient mutants caused by partial loss of mitochondrial deoxyribonucleic acid. Nuclear mutation represented by reversion from Trp- to Trp+ was also...
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