Article
Expressing murine beta 1,4-galactosyltransferase in HeLa cells produces a cell surface galactosyltransferase-dependent phenotype.
The Journal of biological chemistry - 11 Nov 1994
Nguyen T T, Hinton D A, Shur B D
Abstract excerpt
Beta 1,4-Galactosyltransferase is traditionally viewed as a biosynthetic component of the Golgi complex, but a portion of galactosyltransferase is also expressed on the cell surface, where it has been suggested to function as a receptor for extracellular oligosaccharide ligands. Although results...
Topics
- Animals
- Antibodies
- Blotting, Western
- Cell Membrane
- Chromatography, Affinity
- DNA, Complementary
- Electrophoresis, Polyacrylamide Gel
- Epitopes
- Escherichia coli
- Golgi Apparatus
- HeLa Cells
- Humans
- Immunohistochemistry
- Mice
- Molecular Weight
- N-Acetyllactosamine Synthase
- Phenotype
- Recombinant Fusion Proteins