Article
The parallelogram approach in studies of genotoxic effects.
Mutation research - 1 Jan 2000
Anderson D, Sorsa M, Waters M D
Abstract excerpt
Over the past two decades mutagenicity tests have been used for the identification of potential human mutagens and have had an ancillary role, as supportive evidence in the assessment of human carcinogens. The demonstration of human germinal mutagens has been beyond the main scope of short-term testing strategies. However, just as mutagenicity tests have been useful in detecting potential carcinogens so should...
Topics
- Animals
- Biomarkers
- Carcinogenicity Tests
- Carcinogens
- Environmental Exposure
- Genes, Tumor Suppressor
- Humans
- Mice
- Models, Theoretical
- Mutagenicity Tests
- Mutagens
- Mutation