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Article

Application of toxicogenomics to study mechanisms of genotoxicity and carcinogenicity.

Toxicology letters - 10 Apr 2009

Ellinger-Ziegelbauer Heidrun, Aubrecht Jiri, Kleinjans Jos C, Ahr Hans-Juergen

Abstract excerpt

Specific genotoxic events such as gene mutations and/or chromosome damage are considered hallmarks of cancer. The genotoxicity testing battery enables relatively simple, rapid and inexpensive hazard identification, namely by assessing a chemical's ability to cause genetic damage in cells. In addition, the 2-year rodent carcinogenicity bioassay provides an assessment of a risk associated with the chemical to...

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Identifiers

PMID: 18822359
DOI: 10.1016/j.toxlet.2008.08.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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