Article
Epitope specificity determines the ability of anti-Ro52 autoantibodies to precipitate Ro ribonucleoprotein particles.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 1994
Peek R, Pruijn G J, van Venrooij W J
Abstract excerpt
Ro ribonucleoprotein particles (Ro RNPs) are evolutionarily conserved cytoplasmic complexes of unknown function. They are composed of several proteins and a small, RNA polymerase III-transcribed Ro or Y RNA. Abs directed against the protein moiety of Ro RNPs are often found in sera of patients su...
Topics
- Antibodies, Antinuclear
- Autoantigens
- Base Sequence
- Blotting, Northern
- Blotting, Western
- Epitope Mapping
- Epitopes
- Humans
- Molecular Sequence Data
- Mutation
- Precipitin Tests
- Protein Biosynthesis
