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Article

Immunity to Intracellular Salmonella Depends on Surface-associated Antigens

18 Oct 2012

Abstract excerpt

Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum. Novel vaccines with broad serovar coverage are needed, but suitable protective antigens remain largely unknown. Here, we tested 37 broadly conserved Salmonella antigens in a mouse typhoid fever model, and identified antigen candidates that conferred...

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PMID: 23093937
DOI: 10.1371/journal.ppat.1002966

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