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Article

Live attenuated Salmonella: a paradigm of mucosal vaccines

1 Oct 1999

Abstract excerpt

Two key steps control immune responses in mucosal tissues: the sampling and transepithelial transport of antigens, and their targeting into professional antigen-presenting cells in mucosa-associated lymphoid tissue. Live Salmonella bacteria use strategies that allow them to cross the epithelial barrier of the gut, to survive in antigen-presenting cells where bacterial antigens are processed and presented to the...

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Identifiers

PMID: 10582163
DOI: 10.1111/j.1600-065x.1999.tb01340.x

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