Pattern generation in molecular evolution: exploitation of the variation in RNA landscapes.

doi:10.1007/BF00178251

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Article

Pattern generation in molecular evolution: exploitation of the variation in RNA landscapes.

Journal of molecular evolution - 1 Jul 1994

Huynen M A, Hogeweg P

Abstract excerpt

Evolution of RNA secondary structure is studied using simulation techniques and statistical analysis of fitness landscapes. The transition from RNA sequence to RNA secondary structure leads to fitness landscapes that have local variations in their "ruggedness." Evolution exploits these variations...

Topics

Animals
Base Composition
Biological Evolution
Genetic Variation
Models, Genetic
Mutation
Nucleic Acid Conformation
RNA

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