Article
A comparison of genotype-phenotype maps for RNA and proteins.
Biophysical journal - 18 Apr 2012
Ferrada Evandro, Wagner Andreas
Abstract excerpt
The relationship between the genotype (sequence) and the phenotype (structure) of macromolecules affects their ability to evolve new structures and functions. We here compare the genotype space organization of proteins and RNA molecules to identify differences that may affect this ability. To this end, we computationally study the genotype-phenotype relationship for short RNA and lattice proteins of a reduced...
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