Article
Involvement of membrane bleomycin-binding sites in bleomycin cytotoxicity.
Biochemical pharmacology - 19 Jul 1994
Pron G, Belehradek J, Orlowski S, Mir L M
Abstract excerpt
The authors have recently shown the existence of bleomycin (BLM)-binding sites at the surface of DC-3F cells. In order to study the involvement of these sites in the sensitivity of the cells to bleomycin several BLM-resistant cell lines from DC-3F cells were analysed. These mutants were obtained...
Topics
- Animals
- Binding Sites
- Bleomycin
- Carrier Proteins
- Cell Line, Transformed
- Cell Membrane
- Cricetinae
- Cricetulus
- Drug Resistance
- Mutation