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Differential expression of the cell‐cell adhesion molecule E‐cadherin in ascites and solid human ovarian tumor cells

1 Aug 1994

Abstract excerpt

Advanced ovarian cancers contain 2 distinct phenotypic populations: (a) free-floating tumor cells in the ascitic fluid and (b) solid tumors. Ascites cells are derived from the solid tumors and spread throughout the peritoneum. Changes in cell-cell and cell-extracellular matrix interactions are thought to be responsible for the origin of ascites cells. Since E-cadherin molecules play a crucial role in the...

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PMID: 7519585
DOI: 10.1002/ijc.2910580315

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