Article
Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family.
The Journal of biological chemistry - 8 Jul 1994
Fearon K, McClendon V, Bonetti B, Bedwell D M
Abstract excerpt
The requirements for efficient translation termination are incompletely understood. Since the local context surrounding stop codons can influence the efficiency of translation termination, premature termination codons introduced by random mutation may not always terminate at the optimal efficiencies expected of naturally occurring stop codons. To investigate whether this could result in physiologically...
Topics
- ATP-Binding Cassette Transporters
- Adenosine Triphosphate
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Carrier Proteins
- Conserved Sequence
- Cystic Fibrosis Transmembrane Conductance Regulator
- DNA, Fungal
- Fungal Proteins