Epstein-Barr virus positivity in Hodgkin's disease does not correlate with an HLA A2-negative phenotype.

doi:10.1002/1097-0142(19940615)73:12<3059::aid-cncr2820731226>3.0.co;2-q

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Article

Epstein-Barr virus positivity in Hodgkin's disease does not correlate with an HLA A2-negative phenotype.

Cancer - 15 Jun 1994

Poppema S, Visser L

Abstract excerpt

BACKGROUND: Epstein-Barr virus- (EBV) related DNA and RNA can be found in tissues involved with Hodgkin's disease, specifically in the Reed-Sternberg cells. These cells also express the membrane antigens LMP1 and LMP 2A and 2B. Studies in normal individuals indicate that cellular immunity against...

Topics

Base Sequence
DNA, Viral
Female
HLA-A2 Antigen
Herpesvirus 4, Human
Hodgkin Disease
Humans
Male
Molecular Sequence Data
Oligonucleotide Probes
Phenotype
RNA

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