Article
Detection of Epstein-Barr virus and genotyping based on EBNA2 protein in Mexican patients with hodgkin lymphoma: a comparative study in children and adults.
Clinical lymphoma, myeloma & leukemia - 1 Jun 2013
Palma Icela, Sánchez Ana Elena, Jiménez-Hernández Elva, Alvarez-Rodríguez Francisco, Nava-Frias Margarita, Valencia-Mayoral Pedro, Salinas-Lara Citlatepet, Velazquez-Guadarrama Norma, Portilla-Aguilar Josefina, Pena Rocio Y, Ramos-Salazar Patricia, Contreras Alejandra, Alfaro Ana, Espinosa Ana Maria, Nájera Nayelli, Gutierrez Gisela, Mejia-Arangure Juan Manuel, Arellano-Galindo José
Abstract excerpt
BACKGROUND: Epstein-Barr virus (EBV) is a member of the Herpesviridae family and is associated with Hodgkin lymphoma (HL). Isolates of EBV are classified according to sequence variation in the latency genes such as Epstein-Barr virus nuclear antigen (EBNA). EBNA2 contains the most divergent locus and is classified into type 1 and type 2 or EBNA2A and EBNA2B, respectively. We compared the frequency of EBV and the...
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