Article
Distribution and phenotype of Epstein-Barr virus-harboring cells in Hodgkin's disease.
Blood - 15 Jul 1992
Herbst H, Steinbrecher E, Niedobitek G, Young L S, Brooks L, Müller-Lantzsch N, Stein H
Abstract excerpt
Distribution and phenotype of Epstein-Barr virus (EBV)-harboring cells were determined in Hodgkin's disease (HD) biopsies by in situ hybridization with [35S]-labeled RNA probes specific for the small EBV-encoded nuclear RNAs, EBER1 and EBER2, in some instances preceded by immunohistology for CD20, CD30, CD45RO, and CD68 antigens, the T-cell receptor beta-chain, and latent membrane antigen (LMP) of EBV....
Topics
- Antigens, CD
- Antigens, Viral
- Biopsy
- Herpesvirus 4, Human
- Hodgkin Disease
- Humans
- Lymph Nodes
- Phenotype
- Proteins
- RNA Probes
- RNA, Viral
- RNA-Binding Proteins