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Article

Organization and sequence of the HpaII restriction-modification system and adjacent genes.

Gene - 3 May 1994

Kulakauskas S, Barsomian J M, Lubys A, Roberts R J, Wilson G G

Abstract excerpt

We report the organization of the HpaII restriction and modification (R-M) system from Haemophilus parainfluenzae (recognition sequence: 5'...CCGG...3'), the sequence of the gene coding for the HpaII restriction endonuclease, and the sequence of the upstream flanking DNA. The HpaII system comprises two genes, hpaIIM, coding for the methyltransferase (MTase; 358 amino acids (aa), 40.4 kDa: product, Cm5CGG), and...

Topics

Amino Acid Sequence
Base Sequence
Cloning, Molecular
DNA, Bacterial
DNA-Cytosine Methylases
Deoxyribonuclease HpaII
Deoxyribonucleases, Type II Site-Specific
Haemophilus
Molecular Sequence Data
Mutation
Restriction Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Amino Acid

Temperature

Source

Identifiers

PMID: 7514149
DOI: 10.1016/0378-1119(94)90348-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7514149-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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