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Article

Tn10-mediated inversions fuse uridine phosphorylase (udp) and rRNA genes of Escherichia coli.

Journal of bacteriology - 1 Apr 1994

Fonstein M, Nikolskaya T, Zaporojets D, Nikolsky Y, Kulakauskas S, Mironov A

Abstract excerpt

Two strains carrying metE::Tn10 insertions (upstream of the udp gene) were used to isolate mutants of Escherichia coli overexpressing udp. These strains differ in their gene order; one contains an inversion between the rrnD and rrnE rRNA operons. Selection was based on the ability of overexpressed Udp to complement thymine auxotrophy. Chromosomal rearrangements that connect the udp gene and promoters of different...

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Identifiers

PMID: 7512551
DOI: 10.1128/jb.176.8.2265-2271.1994
PMCID: PMC205348

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