An efficient Shine-Dalgarno sequence but not translation is necessary for lacZ mRNA stability in Escherichia coli.

doi:10.1128/jb.176.6.1683-1688.1994

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Article

An efficient Shine-Dalgarno sequence but not translation is necessary for lacZ mRNA stability in Escherichia coli.

Journal of bacteriology - 1 Mar 1994

Wagner L A, Gesteland R F, Dayhuff T J, Weiss R B

Abstract excerpt

The 5' ends of many bacterial transcripts are important in determining mRNA stability. A series of Shine-Dalgarno (SD) sequence changes showed that the complementarity of the SD sequence to the anti-SD sequence of 16S rRNA correlates with lacZ mRNA stability in Escherichia coli. Several initiatio...

Topics

Codon
DNA, Bacterial
Escherichia coli
Lac Operon
Molecular Sequence Data
Mutation
Protein Biosynthesis
RNA, Bacterial
RNA, Messenger
Ribosomes

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