Article
Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence.
Scientific reports - 24 Apr 2015
Sudhir Putty-Reddy, Lin Shiu-Ting, Chia-Wen Chien, Yang Shung-Haur, Li Anna Fen-Yau, Lai Rai-Hua, Wang Mei-Jung, Chen Yuan-Tsong, Chen Chian-Feng, Jou Yuh-Shan, Chen Jeou-Yuan
Abstract excerpt
Identification and functional analysis of genes from genetically altered chromosomal regions would suggest new molecular targets for cancer diagnosis and treatment. Here we performed a genome-wide analysis of chromosomal copy number alterations (CNAs) in matching sets of colon mucosa-adenoma-carcinoma samples using high-throughput oligonucleotide microarray analysis. In silico analysis of NCBI GEO and TCGA...
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