Article
Effect of competitive antagonism of NO synthetase on weight and food intake in obese and diabetic mice.
The American journal of physiology - 1 Jan 1994
Morley J E, Flood J F
Abstract excerpt
Recent studies have suggested a role for nitric oxide (NO) in the regulation of food intake. The present studies were undertaken to examine the effects of the administration of a nitric oxide synthetase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME), on food intake and weight loss. Two gene...
Topics
- Amino Acid Oxidoreductases
- Analysis of Variance
- Animals
- Blood Glucose
- Body Weight
- Diabetes Mellitus, Experimental
- Dose-Response Relationship, Drug
- Eating
- Genotype
- Male
- Mice
- Mice, Mutant Strains
- Nitric Oxide Synthase
- Obesity