Article
Bidirectional effects of clonidine on carbohydrate intake in genetically obese (ob/ob) mice.
Pharmacology, biochemistry, and behavior - 1 Jan 1991
Currie P J, Wilson L M
Abstract excerpt
Hypothalamic noradrenergic mechanisms contribute to altered caloric intake in genetically obese (C57BL/6J, ob/ob) mice. Noradrenergic mechanisms, principally in the paraventricular hypothalamus and of the alpha 2 subtype, have also been implicated in the macronutrient intake regulation of nonpathological models. Accordingly, this study assessed the extent to which clonidine, an alpha 2 agonist, altered...
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