Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bidirectional effects of clonidine on carbohydrate intake in genetically obese (ob/ob) mice.

Pharmacology, biochemistry, and behavior - 1 Jan 1991

Currie P J, Wilson L M

Abstract excerpt

Hypothalamic noradrenergic mechanisms contribute to altered caloric intake in genetically obese (C57BL/6J, ob/ob) mice. Noradrenergic mechanisms, principally in the paraventricular hypothalamus and of the alpha 2 subtype, have also been implicated in the macronutrient intake regulation of nonpathological models. Accordingly, this study assessed the extent to which clonidine, an alpha 2 agonist, altered...

Topics

Animals
Body Weight
Clonidine
Diet
Dietary Carbohydrates
Dietary Fats
Dietary Proteins
Energy Intake
Feeding Behavior
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Obesity

Phenotype

Source

Identifiers

PMID: 2017443
DOI: 10.1016/0091-3057(91)90607-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2017443-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bidirectional effects of clonidine on carbohydrate intake in genetically obese (ob/ob) mice.PMID 2017443Read ↗

Potentiation of dark onset feeding in obese mice (genotype ob/ob) following central injection of norepinephrine and clonidine.Semantic proximity Read ↗

Feeding microstructure in diet-induced obesity susceptible versus resistant rats: central effects of urocortin 2.Semantic proximity Read ↗

Pro-Opiomelanocortin Modulates the Thermogenic and Physical Activity Responses to High-Fat Feeding and Markedly Influences Dietary Fat PreferenceSemantic proximity Read ↗

The Role of Endogenous Beta-Endorphin in Food Intake and Glucose Homeostasis in Male and Female Mice Fed a High-Fat DietSemantic proximity Read ↗

High intake of palatable food predicts binge-eating independent of susceptibility to obesity: an animal model of lean vs obese binge-eating and obesity with and without binge-eating.Semantic proximity Read ↗

Diet Protein Content and Individual Phenotype Affect Food Intake and Protein Appetence in Rats.Semantic proximity Read ↗

Pharmacological modulation of dopamine receptor D2-mediated transmission alters the metabolic phenotype of diet induced obese and diet resistant C57Bl6 mice.Semantic proximity Read ↗

Alterations in activity and energy expenditure contribute to lean phenotype in Fischer 344 rats lacking the cholecystokinin-1 receptor gene.Semantic proximity Read ↗

Repeated binge access to a palatable food alters feeding behavior, hormone profile, and hindbrain c-Fos responses to a test meal in adult male rats.Semantic proximity Read ↗

Genetic variance contributes to ingestive processes: a survey of 2-deoxy-D-glucose-induced feeding in eleven inbred mouse strains.Semantic proximity Read ↗

Divergent effect of dehydroepiandrosterone on energy intakes of Zucker rats.Semantic proximity Read ↗

Genetic variation affects binge feeding behavior in female inbred mouse strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.