The Golgi guanosine diphosphatase is required for transport of GDP-mannose into the lumen of Saccharomyces cerevisiae Golgi vesicles.

Article

The Golgi guanosine diphosphatase is required for transport of GDP-mannose into the lumen of Saccharomyces cerevisiae Golgi vesicles.

The Journal of biological chemistry - 7 Jan 1994

Berninsone P, Miret J J, Hirschberg C B

Abstract excerpt

The Saccharomyces cerevisiae Golgi lumenal guanosine diphosphatase is hypothesized to generate GMP which in turn allows entry of GDP-mannose into the lumen to serve as substrate for mannosylation of proteins and lipids. We have recently shown in studies in vivo that this GDPase is required for pr...

Topics

Biological Transport
Golgi Apparatus
Guanosine Diphosphate Mannose
Mannosyltransferases
Mutation
Pyrophosphatases
Saccharomyces cerevisiae

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