Article
Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.
The Journal of biological chemistry - 9 Oct 1998
Rayner J C, Munro S
Abstract excerpt
The mannan structure found on the N-linked glycans of the yeast Saccharomyces cerevisiae is composed of a long backbone of alpha-1, 6-linked mannose to which are attached branches consisting of two alpha-1,2-linked mannoses followed by an alpha-1,3-linked mannose. In the mutants mnn2 and mnn5, th...
Topics
- Amino Acid Sequence
- Carbohydrate Conformation
- Glycosylation
- Mannans
- Mannosyltransferases
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- Saccharomyces cerevisiae
- Sequence Deletion
- Sequence Homology, Amino Acid