Article
Identification of a conserved motif in the yeast golgi GDP-mannose transporter required for binding to nucleotide sugar.
The Journal of biological chemistry - 9 Feb 2001
Gao X D, Nishikawa A, Dean N
Abstract excerpt
Glycoproteins and lipids in the Golgi complex are modified by the addition of sugars. In the yeast Saccharomyces cerevisiae, these terminal Golgi carbohydrate modifications primarily involve mannose additions that utilize GDP-mannose as the substrate. The transport of GDP-mannose from its site of synthesis in the cytosol into the lumen of the Golgi is mediated by the VRG4 gene product, a nucleotide sugar...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.