Article
Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins.
The EMBO journal - 1 Sept 1990
Nehlin J O, Ronne H
Abstract excerpt
We have cloned a yeast gene, MIG1, which encodes a C2H2 zinc finger protein involved in glucose repression. The fingers of MIG1 are very similar to those present in the mammalian Egr finger proteins, which are induced during the early growth response, and also to the finger protein encoded by a human gene that is deleted in Wilms' tumour cells. MIG1 protein binds to two sites in the upstream region of SUC2, a...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Deletion
- DNA-Binding Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genotype
- Glucose
- Humans
- Kidney Neoplasms
- Metalloproteins
