Article
Drosophila Ten-m and filamin affect motor neuron growth cone guidance.
PloS one - 1 Jan 2011
Zheng Lihua, Michelson Yehudit, Freger Vita, Avraham Ziva, Venken Koen J T, Bellen Hugo J, Justice Monica J, Wides Ron
Abstract excerpt
The Drosophila Ten-m (also called Tenascin-major, or odd Oz (odz)) gene has been associated with a pair-rule phenotype. We identified and characterized new alleles of Drosophila Ten-m to establish that this gene is not responsible for segmentation defects but rather causes defects in motor neuron axon routing. In Ten-m mutants the inter-segmental nerve (ISN) often crosses segment boundaries and fasciculates with...
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