Article
Host and phi X 174 mutations affecting the morphogenesis or stabilization of the 50S complex, a single-stranded DNA synthesizing intermediate.
Genetics - 1 Aug 1995
Ekechukwu M C, Oberste D J, Fane B A
Abstract excerpt
The morphogenetic pathway of bacteriophage phi X 174 was investigated in rep mutant hosts that specifically block stage III single-stranded DNA synthesis. The defects conferred by the mutant rep protein most likely affect the formation or stabilization of the 50S complex, a single-stranded DNA sy...
Topics
- Bacterial Proteins
- Bacteriophage phi X 174
- Capsid
- DNA Helicases
- DNA Replication
- DNA, Single-Stranded
- DNA, Viral
- DNA-Binding Proteins
- Escherichia coli
- Genes, Bacterial
- Genes, Viral
- Macromolecular Substances
- Models, Biological
- Morphogenesis
- Mutation
- Peptide Initiation Factors
- Protein Conformation
- Suppression, Genetic