Structural basis for bacteriophage phi X174 assembly and eclipse as defined by temperature-sensitive mutations.

doi:10.1006/viro.1993.1533

Back to search

Article

Structural basis for bacteriophage phi X174 assembly and eclipse as defined by temperature-sensitive mutations.

Virology - 1 Oct 1993

Ilag L L, Incardona N L

Abstract excerpt

We present a screening procedure for classifying bacteriophage phi X174 mutants as defective in either "early" (genome delivery and RF DNA replication) or "late" (progeny ssDNA replication and morphogenesis) functions. When applied to 108 ts mutants, only five were classified as "early" mutants....

Topics

Bacteriophage phi X 174
DNA, Viral
Hot Temperature
Models, Molecular
Mutation
Phenotype
Restriction Mapping
Sequence Analysis, DNA
Time Factors
Transfection
Viral Plaque Assay
Virus Replication

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.