Linkage and the limits to natural selection.

doi:10.1093/genetics/140.2.821

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Article

Linkage and the limits to natural selection.

Genetics - 1 Jun 1995

Barton N H

Abstract excerpt

The probability of fixation of a favorable mutation is reduced if selection at other loci causes inherited variation in fitness. A general method for calculating the fixation probability of an allele that can find itself in a variety of genetic backgrounds is applied to find the effect of substit...

Topics

Genetic Linkage
Models, Genetic
Mutation
Selection, Genetic

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