Article
On the Consequences of Purging and Linkage on Fitness and Genetic Diversity.
G3 (Bethesda, Md.) - 12 Nov 2015
Bersabé Diego, Caballero Armando, Pérez-Figueroa Andrés, García-Dorado Aurora
Abstract excerpt
Using computer simulation we explore the consequences of linkage on the inbreeding load of an equilibrium population, and on the efficiency of purging and the loss of genetic diversity after a reduction in population size. We find that linkage tends to cause increased inbreeding load due to the build up of coupling groups of (partially) recessive deleterious alleles. It also induces associative overdominance at...
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