Article
Microsatellite instability in human colonic cancer is not a useful clinical indicator of familial colorectal cancer.
Gastroenterology - 1 Dec 1995
Samowitz W S, Slattery M L, Kerber R A
Abstract excerpt
BACKGROUND & AIMS: Microsatellite instability is a property of most tumors occurring in the context of hereditary nonpolyposis colon cancer. Instability also occurs in 10%-15% of apparently sporadic colorectal cancers, and it has been hypothesized that this instability may indicate a genetic predisposition to colonic cancer. This study evaluated whether there is a clinically useful association between colon...
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