Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire.

Journal of virology - 1 Dec 1995

Daly K, Nguyen P, Woodland D L, Blackman M A

Abstract excerpt

We have used T-cell receptor beta-chain transgenic mice to determine the effects of a limited T-cell receptor repertoire on major histocompatibility complex class I-restricted epitope selection during the course of an influenza virus infection. Analysis of T-cell hybridomas generated from wild-type and transgenic mice demonstrated that the viral epitope recognized depended on the available T-cell receptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Epitopes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-2

Share to Mice, Transgenic

Share to Molecular Sequence Data

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 7494246
DOI: 10.1128/JVI.69.12.7416-7422.1995
PMCID: PMC189678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire.PMID 7494246Read ↗

Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex.Semantic proximity Read ↗

Immunodominance correlates with T-cell receptor (alpha beta) gene usage in the class II-restricted response to influenza haemagglutinin.Semantic proximity Read ↗

Preferential selection of receptor-binding variants of influenza virus hemagglutinin by the neutralizing antibody repertoire of transgenic mice expressing a human immunoglobulin mu minigene.Semantic proximity Read ↗

Application of Humanized MHC Transgenic Mice in the Screening of HLA–Restricted T Cell Epitopes for Influenza VaccinesSemantic proximity Read ↗

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function.Semantic proximity Read ↗

The immunodominant influenza matrix t cell epitope recognized in human induces influenza protection in HLA-A2/Kb transgenic miceSemantic proximity Read ↗

Competition between MHC class I alleles for cell surface expression alters CTL responses to influenza A virus.Semantic proximity Read ↗

HLA-B*0702 transgenic, H-2KbDb double-knockout mice: phenotypical and functional characterization in response to influenza virus.Semantic proximity Read ↗

Fixed expression of single influenza virus-specific TCR chains demonstrates the capacity for TCR α- and β-chain diversity in the face of peptide-MHC class I specificity.Semantic proximity Read ↗

Heterotypic immunity against vaccinia virus in an HLA-B*07:02 transgenic mousepox infection modelSemantic proximity Read ↗

The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model.Semantic proximity Read ↗

T-cell receptors from virus-specific cytotoxic T lymphocytes recognizing a single immunodominant nine-amino-acid viral epitope show marked diversity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.