Article
Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire.
Journal of virology - 1 Dec 1995
Daly K, Nguyen P, Woodland D L, Blackman M A
Abstract excerpt
We have used T-cell receptor beta-chain transgenic mice to determine the effects of a limited T-cell receptor repertoire on major histocompatibility complex class I-restricted epitope selection during the course of an influenza virus infection. Analysis of T-cell hybridomas generated from wild-ty...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Bronchoalveolar Lavage Fluid
- Cytotoxicity, Immunologic
- Epitopes
- Genes, MHC Class I
- Histocompatibility Antigens Class I
- Hybridomas
- Influenza A virus
- Interleukin-2
- L Cells
- Lymph Nodes
- Mice
- Mice, Inbred CBA