Article
[Deletion polymorphism of the angiotensin I-converting enzyme gene associates with increased risk for ischemic heart diseases in the Japanese].
Rinsho byori. The Japanese journal of clinical pathology - 1 Jul 1994
Nakai K, Itoh C, Miura Y, Musya T, Hotta K, Hiramori K
Abstract excerpt
The Angiotensin I-converting enzyme (ACE) is a key component of the renin-angiotensin system thought to be important in the pathogenesis of hypertension and cardiovascular diseases. Previous studies showed that deletion polymorphism in the ACE gene might be a risk factor for myocardial infarction in the Caucasian population. However, this finding has not yet been reported in the Japanese population. In this...
Topics
- Adult
- Aged
- Angiotensin I
- Base Sequence
- Cross-Sectional Studies
- Gene Deletion
- Genotype
- Humans
- Japan
- Middle Aged
- Molecular Sequence Data