Article
Angiotensin-converting enzyme deletion polymorphism is associated with hypertension in a Sikh population.
Human heredity - 1 Jan 2000
Mastana S, Nunn J
Abstract excerpt
The deletion polymorphism, situated in intron 16, of angiotensin-converting enzyme (ACE) gene (17q23) has been observed to be associated with an increased risk for myocardial infarction and left ventricular hypertrophy in Caucasian populations. The homozygous genotype for the deletion allele (DD) has additionally been observed at greater frequencies in hypertensive individuals of African-American and Japanese...
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