Article
Different allele distribution of a regulatory MAOA gene promoter polymorphism in antisocial and anxious-depressive alcoholics.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2000
Schmidt L G, Sander T, Kuhn S, Smolka M, Rommelspacher H, Samochowiec J, Lesch K P
Abstract excerpt
Heritable factors account for approximately 40-60% of the total variance of liability to alcohol dependence. The present study tested whether a novel functional polymorphism in the promotor region of the X-chromosomal monoamine oxidase A gene (MAOA) was related to antisocial and anxious-depressive traits in alcoholics. Due to the X-chromosomal localization of the MAOA gene, psychobiological traits were compared...
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