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Article

Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14.

American journal of medical genetics - 27 Feb 1995

Mullan M, Bennett C, Figueredo C, Hughes D, Mant R, Owen M, Warren A, McInnis M, Marshall A, Lantos P

Abstract excerpt

Early onset familial Alzheimer's disease (AD) has an autosomal dominant mode of inheritance. Two genes are responsible for the majority of cases of this subtype of AD. Mutations in the beta-amyloid precursor protein (beta APP) gene on chromosome 21 have been shown to completely cosegregate with the disease. We and others have previously described the clinical features of families with beta APP mutations at the...

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Source

Identifiers

PMID: 7485234
DOI: 10.1002/ajmg.1320600109

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14.PMID 7485234Read ↗

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