Article
Angiotensin I-converting enzyme gene polymorphism enhances the effect of hypercholesterolemia on the risk of coronary heart disease in a general Japanese population: the hisayama study.
Journal of atherosclerosis and thrombosis - 1 Jan 2015
Kondo Hideki, Ninomiya Toshiharu, Hata Jun, Hirakawa Yoichiro, Yonemoto Koji, Arima Hisatomi, Nagata Masaharu, Tsuruya Kazuhiko, Kitazono Takanari, Kiyohara Yutaka
Abstract excerpt
AIM: The angiotensin I-converting enzyme (ACE) insertion (I)/deletion (D) polymorphism has been reported to be implicated in susceptibility to coronary heart disease (CHD). However, this association remains inconclusive. The purpose of this study was to clarify the association between the I/D polymorphism of the ACE gene and the development of CHD in a Japanese general population and investigate whether the...
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