Article
Angiotensinogen gene polymorphism in Japanese patients with hypertrophic cardiomyopathy.
American heart journal - 1 Feb 1997
Ishanov A, Okamoto H, Yoneya K, Watanabe M, Nakagawa I, Machida M, Onozuka H, Mikami T, Kawaguchi H, Hata A, Kondo K, Kitabatake A
Abstract excerpt
To examine the contribution of the renin-angiotensin system to hypertrophic cardiomyopathy (HCM), we studied 96 patients with HCM (mean age 50 years, 55% male), 105 of their unaffected siblings and offspring, and 160 healthy subjects without known hypertension and left ventricular hypertrophy (LVH) who were frequency matched to cases by age and sex. Patients were divided into familial or sporadic HCM (FHCM or...
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